Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.53 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28417334 | 0.98 | PARP1 (0.52) | PARP1SLC7A5ADRB2ADRB1ADRB3 | |
| SCHEMBL8111051 | 0.90 | SLC7A5 (0.48) | PARP1SLC7A5ADRB2ADRB1ADRB3 | |
| SCHEMBL110296 | 0.88 | SLC7A5 (0.58) | SLC7A5ESR1ESR2CYP2C19CYP1A2 | |
| Hydrogen Peroxide SCHEMBL27146001 | 0.86 | SLC7A5 (0.60) | SLC7A5ESR1ESR2RAB9ACYP2C19 | |
| SCHEMBL28350987 | 0.86 | SLC7A5 (0.56) | SLC7A5ESR1ESR2CYP2C19CYP1A2 | |
| Water SCHEMBL28897664 | 0.86 | SLC7A5 (0.56) | SLC7A5ESR1ESR2CYP2C19CYP1A2 | |
| SCHEMBL1505170 | 0.84 | PARP1 (0.52) | PARP1ADRB2ADRB1ADRB3HDAC8 | |
| SCHEMBL7385096 | 0.82 | GPR17 (0.51) | PARP1ADRB2ADRB1ADRB3HDAC8 | |
| SCHEMBL27642696 | 0.82 | PARP1 (0.47) | PARP1SLC7A5ADRB2ADRB1ADRB3 | |
| SCHEMBL23037380 | 0.82 | TDP1 (0.66) | PARP1ADRB2ADRB1ADRB3HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3692101-B1 | BRILLIANT BLUE (BBG) DYE DERIVATIVES AND STAINING COMPOSITIONS COMPRISING THE SAME FOR SELECTIVELY STAINING BIOLOGICAL SUBSTRATES | ALFA INSTR S R L (IT) | 2022-01-12 | — | — | EP | claimed |
| EP-3692101-A1 | BRILLIANT BLUE (BBG) DYE DERIVATIVES AND STAINING COMPOSITIONS COMPRISING THE SAME FOR SELECTIVELY STAINING BIOLOGICAL SUBSTRATES | Alfa Instruments S.r.l. (IT) | 2020-08-12 | — | — | EP | claimed |
| CN-107848222-B | The method of modified olefine polymer is prepared in an extruder | 博里利斯股份公司 | 2019-08-27 | — | — | CN | claimed |
| WO-2019068935-A1 | BRILLIANT BLUE (BBG) DYE DERIVATIVES AND STAINING COMPOSITIONS COMPRISING THE SAME FOR SELECTIVELY STAINING BIOLOGICAL SUBSTRATES | ALFA INSTRUMENTS S.R.L. (IT) | 2019-04-11 | — | — | WO | claimed |
| CN-107848222-A | The method for preparing modified olefine polymer in an extruder | 博里利斯股份公司 | 2018-03-27 | — | — | CN | claimed |
| CN-107538000-A | The method of metal casting magnetic modified nanometer methacrylate magnetic impregnant | 初丽萍 | 2018-01-05 | — | — | CN | claimed |
| CN-107459936-A | A kind of methacrylate esters impregnation liquid containing epoxy resin | 苏州纳康纳米材料有限公司 | 2017-12-12 | — | — | CN | claimed |
| CN-105921725-B | Preparation method of magnetic nano modified methacrylate magnetic impregnant for metal castings | 南京旭羽睿材料科技有限公司 | 2017-12-08 | — | — | CN | claimed |
| CN-106046266-A | Epoxy monomer-comprising methacrylate impregnant for metal castings | 初丽萍 | 2016-10-26 | — | — | CN | claimed |
| CN-105921725-A | Method for magnetic nano modified methacrylate magnetic impregnant for metal casting | 初丽萍 | 2016-09-07 | — | — | CN | claimed |
| CN-100555476-C | No-halogen fire-resistant radiation cross-link wire and preparation method thereof | SHENZHEN WOER NUCLEAR MATERIAL (CN) | 2009-10-28 | — | — | CN | claimed |
| CN-1758385-A | No-halogen fire-resistant radiation cross-link wire and its preparation method | SHENZHEN WOER NUCLEAR MATERIAL (CN) | 2006-04-12 | — | — | CN | claimed |
| WO-2023235753-A2 | ALDH2 INHIBITORS AND METHODS OF USE THEREOF | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2023-12-07 | — | — | WO | disclosed |
| WO-2023022497-A1 | SOS1 INHIBITOR AND USE THEREOF | 주식회사 카나프테라퓨틱스 | 2023-02-23 | — | — | WO | disclosed |
| EP-3692101-B1 | BRILLIANT BLUE (BBG) DYE DERIVATIVES AND STAINING COMPOSITIONS COMPRISING THE SAME FOR SELECTIVELY STAINING BIOLOGICAL SUBSTRATES | ALFA INSTR S R L (IT) | 2022-01-12 | — | — | EP | disclosed |
| EP-3692101-A1 | BRILLIANT BLUE (BBG) DYE DERIVATIVES AND STAINING COMPOSITIONS COMPRISING THE SAME FOR SELECTIVELY STAINING BIOLOGICAL SUBSTRATES | Alfa Instruments S.r.l. (IT) | 2020-08-12 | — | — | EP | disclosed |
| US-5508437-A | APPETITE SUPPRESSANTS | HOFFMANN-LA ROCHE INC. (US) | 1996-04-16 | — | — | US | disclosed |
| US-5296608-A | Intermediates for analogs of tyrosine sulfate or tyrosine phosphate containing peptides | HOFFMAN-LA ROCHE INC. (US) | 1994-03-22 | — | — | US | disclosed |
| US-5182263-A | Appetite suppressants | HOFFMANN-LA ROCHE INC. (US) | 1993-01-26 | — | — | US | disclosed |
| EP-0339549-A2 | Tyr-peptide analogs | F. HOFFMANN-LA ROCHE AG (CH) | 1989-11-02 | — | — | EP | disclosed |