Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 17/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.36 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15599202 | 0.91 | SCN9A (0.43) | SCN9ADPP4SCN5ASCN7AGPR119 | |
| SCHEMBL16771098 | 0.90 | SCN9A (0.42) | SCN9ADPP4SCN5ASCN7AGPR119 | |
| SCHEMBL16759482 | 0.90 | SCN9A (0.42) | SCN9ADPP4SCN5ASCN7A | |
| SCHEMBL17061758 | 0.84 | SCN9A (0.48) | SCN9ASCN5ASCN7AGPR119 | |
| SCHEMBL16758838 | 0.82 | SCN9A (0.40) | SCN9ADPP4SCN5ASCN7A | |
| SCHEMBL15599293 | 0.81 | SCN9A (0.71) | SCN9ASCN5ASCN7A | |
| SCHEMBL21825339 | 0.81 | SCN9A (0.45) | SCN9ADPP4SCN5ASCN7AGPR119 | |
| SCHEMBL17061856 | 0.81 | SCN9A (0.45) | SCN9ADPP4SCN5ASCN7AGPR119 | |
| SCHEMBL17069401 | 0.81 | SCN9A (0.45) | SCN9ADPP4SCN5ASCN7AGPR119 | |
| SCHEMBL17061857 | 0.81 | SCN9A (0.45) | SCN9ADPP4SCN5ASCN7AGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3166939-B1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | GENENTECH INC (US) | 2019-06-05 | — | — | EP | disclosed |