Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 20/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.34 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21075628 | 0.89 | SCN9A (0.43) | SCN9ASCN5A | |
| SCHEMBL21075394 | 0.87 | SCN9A (0.48) | SCN9ASCN5ASCN7A | |
| SCHEMBL23861726 | 0.78 | SCN9A (0.43) | SCN9ASCN5A | |
| SCHEMBL20403793 | 0.77 | SCN9A (0.33) | SCN9ASCN5ASCN7A | |
| SCHEMBL21075351 | 0.77 | SCN9A (0.48) | SCN9ASCN5ASCN7A | |
| SCHEMBL21075163 | 0.73 | SCN9A (0.47) | SCN9ASCN5ASCN7A | |
| SCHEMBL21075109 | 0.73 | SCN9A (0.42) | SCN9ASCN5A | |
| SCHEMBL21075393 | 0.73 | SCN9A (0.60) | SCN9ASCN5ASCN7A | |
| SCHEMBL18570792 | 0.72 | SCN9A (0.39) | SCN9ASCN5A | |
| SCHEMBL18571359 | 0.72 | SCN9A (0.41) | SCN9ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3166939-B1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | GENENTECH INC (US) | 2019-06-05 | — | — | EP | disclosed |