Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 20/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21075625 | 0.83 | SCN9A (0.51) | SCN9ASCN5A | |
| SCHEMBL21075583 | 0.83 | SCN9A (0.47) | SCN9ASCN5A | |
| SCHEMBL21075573 | 0.82 | SCN9A (0.51) | SCN9ASCN5A | |
| SCHEMBL21075644 | 0.81 | SCN9A (0.44) | SCN9ASCN5A | |
| SCHEMBL21075548 | 0.80 | SCN9A (0.54) | SCN9ASCN5A | |
| SCHEMBL21075701 | 0.80 | SCN9A (0.62) | SCN9ASCN5A | |
| SCHEMBL21075171 | 0.79 | CNR2 (0.50) | SCN9ASCN5A | |
| SCHEMBL21075409 | 0.78 | SCN9A (0.47) | SCN9ASCN5A | |
| SCHEMBL21075563 | 0.73 | SCN9A (0.44) | SCN9ASCN5A | |
| SCHEMBL21075442 | 0.72 | SCN9A (0.44) | SCN9ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3166939-B1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | GENENTECH INC (US) | 2019-06-05 | — | — | EP | disclosed |