Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 10/20 | 0.62 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17423164 | 0.89 | SCN9A (0.64) | SCN9ASCN7ASCN5A | |
| SCHEMBL17428454 | 0.89 | SCN9A (0.64) | SCN9ASCN7ASCN5A | |
| SCHEMBL17428730 | 0.86 | SCN9A (0.63) | SCN9ASCN7ASCN5A | |
| SCHEMBL17423344 | 0.86 | SCN9A (0.63) | SCN9ASCN7ASCN5A | |
| SCHEMBL21075477 | 0.85 | SCN9A (0.69) | SCN9ASCN7ASCN5A | |
| SCHEMBL19075785 | 0.83 | SCN9A (0.59) | SCN9ASCN7ASCN5A | |
| SCHEMBL15543440 | 0.82 | SCN9A (0.68) | SCN9ASCN7ASCN5A | |
| SCHEMBL17428627 | 0.80 | SCN9A (0.67) | SCN9ASCN7ASCN5A | |
| SCHEMBL15599056 | 0.78 | SCN9A (0.64) | SCN9ASCN7ASCN5A | |
| SCHEMBL17423179 | 0.77 | SCN9A (0.57) | SCN9ASCN7ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3166939-B1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | GENENTECH INC (US) | 2019-06-05 | — | — | EP | disclosed |