Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 11/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | PYGL | P06737 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20680118 | 0.84 | SCN9A (0.64) | SCN9AFFAR1FFAR4PYGLSCN5A | |
| SCHEMBL19064937 | 0.84 | SCN9A (0.64) | SCN9AFFAR1FFAR4PYGLSCN5A | |
| SCHEMBL17428406 | 0.84 | SCN9A (0.64) | SCN9AFFAR1FFAR4PYGLSCN5A | |
| SCHEMBL17428627 | 0.79 | SCN9A (0.67) | SCN9AFFAR4SCN1ASCN5ASCN2A | |
| SCHEMBL15543440 | 0.78 | SCN9A (0.68) | SCN9AFFAR4SCN1ASCN5ASCN2A | |
| SCHEMBL17422975 | 0.75 | SCN9A (0.64) | SCN9AFFAR1SCN1ASCN5ASCN2A | |
| SCHEMBL17422979 | 0.75 | SCN9A (0.64) | SCN9AFFAR1SCN1ASCN5ASCN2A | |
| SCHEMBL21075815 | 0.74 | SCN9A (0.64) | SCN9AFFAR4SCN5A | |
| SCHEMBL20697703 | 0.74 | SCN9A (0.58) | SCN9AFFAR1FFAR4SCN1ASCN5A | |
| SCHEMBL21075357 | 0.74 | SCN9A (0.62) | SCN9ASCN1ASCN5ASCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3166939-B1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | GENENTECH INC (US) | 2019-06-05 | — | — | EP | disclosed |