Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.44 |
| ▸ | PEPD | P12955 | 1/20 | 0.44 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | XPNPEP2 | O43895 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.38 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9415825 | 0.83 | DPP4 (0.47) | DPP4DPP8DPP9PEPDXPNPEP1 | |
| SCHEMBL11449104 | 0.82 | ACE (0.56) | PEPDACE | |
| SCHEMBL11449103 | 0.82 | ACE (0.56) | PEPDACE | |
| SCHEMBL11450764 | 0.82 | ACE (0.56) | PEPDACE | |
| SCHEMBL4251344 | 0.80 | ATM (0.65) | DPP4DPP8DPP9PIK3CDATM | |
| SCHEMBL4251347 | 0.80 | ATM (0.65) | DPP4DPP8DPP9PIK3CDATM | |
| SCHEMBL4254807 | 0.80 | ATM (0.65) | DPP4DPP8DPP9PIK3CDATM | |
| SCHEMBL4254805 | 0.80 | ATM (0.65) | DPP4DPP8DPP9PIK3CDATM | |
| SCHEMBL4255717 | 0.80 | ATM (0.65) | DPP4DPP8DPP9PIK3CDATM | |
| SCHEMBL12112073 | 0.80 | ATM (0.65) | DPP4DPP8DPP9PIK3CDATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3166939-B1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | GENENTECH INC (US) | 2019-06-05 | — | — | EP | disclosed |