Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19755633 | 1.00 | HRH3 (0.32) | HRH3 | |
| SCHEMBL19755636 | 0.93 | HRH3 (0.32) | HRH3 | |
| SCHEMBL19755637 | 0.90 | HRH3 (0.34) | HRH3 | |
| SCHEMBL17827391 | 0.90 | HRH3 (0.31) | HRH3 | |
| SCHEMBL19353348 | 0.88 | — | — | |
| SCHEMBL19755634 | 0.87 | HRH3 (0.32) | HRH3 | |
| SCHEMBL24817964 | 0.84 | HRH3 (0.33) | HRH3 | |
| SCHEMBL14524119 | 0.84 | HRH3 (0.33) | HRH3 | |
| SCHEMBL23080341 | 0.83 | — | — | |
| SCHEMBL19755635 | 0.81 | HRH3 (0.34) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023071973-A1 | FUSED BICYCLIC COMPOUND FOR INHIBITING ACTIVITY OF TYROSINE KINASE | SHENZHEN TARGETRX, INC. (CN) | 2023-05-04 | — | — | WO | disclosed |
| EP-3492471-B1 | FUSED BICYCLIC COMPOUND FOR INHIBITING ACTIVITY OF TYROSINE KINASE | SHENZHEN TARGETRX INC (CN) | 2020-12-02 | — | — | EP | disclosed |
| EP-3492471-A1 | FUSED BICYCLIC COMPOUND FOR INHIBITING ACTIVITY OF TYROSINE KINASE | Shenzhen Targetrx, Inc. (CN) | 2019-06-05 | — | — | EP | disclosed |