⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18557327 | 0.76 | — | — | |
| SCHEMBL171866 | 0.74 | MAPK1 (0.33) | — | |
| SCHEMBL24050001 | 0.74 | — | — | |
| SCHEMBL24434512 | 0.74 | HTT (0.31) | — | |
| SCHEMBL10332121 | 0.71 | MAPK1 (0.33) | — | |
| SCHEMBL6181705 | 0.71 | MAPK1 (0.33) | — | |
| SCHEMBL24051495 | 0.70 | — | — | |
| SCHEMBL27432351 | 0.70 | — | — | |
| SCHEMBL5699322 | 0.69 | — | — | |
| SCHEMBL14904098 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10933139-B2 | Conjugated lipomers and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-03-02 | — | — | US | disclosed |
| US-20190167795-A1 | CONJUGATED LIPOMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-06-06 | — | — | US | disclosed |