⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24066712 | 0.76 | — | — | |
| SCHEMBL29305583 | 0.75 | — | — | |
| SCHEMBL18134037 | 0.73 | — | — | |
| SCHEMBL20440778 | 0.73 | — | — | |
| SCHEMBL25777362 | 0.73 | — | — | |
| SCHEMBL19832048 | 0.73 | — | — | |
| SCHEMBL21504753 | 0.71 | — | — | |
| SCHEMBL18519067 | 0.70 | — | — | |
| SCHEMBL20844149 | 0.69 | — | — | |
| SCHEMBL22942016 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10695348-B2 | Sulfonyl pyridyl TRP inhibitors | GENENTECH, INC. (US) | 2020-06-30 | — | — | US | disclosed |
| US-20190167681-A1 | SULFONYL PYRIDYL TRP INHIBITORS | GENENTECH, INC. (US) | 2019-06-06 | — | — | US | disclosed |