Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 7/20 | 0.46 |
| ▸ | PTGES | O14684 | 11/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | BCR | P11274 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21044289 | 0.84 | CTPS1 (0.60) | CTPS1 | |
| SCHEMBL21076874 | 0.79 | CTPS1 (0.45) | CTPS1ABL1PTGS2 | |
| SCHEMBL21077111 | 0.78 | CTPS1 (0.46) | CTPS1 | |
| SCHEMBL21044519 | 0.75 | CTPS1 (0.56) | CTPS1 | |
| SCHEMBL22762461 | 0.75 | CTPS1 (0.55) | CTPS1 | |
| SCHEMBL29566729 | 0.74 | CTPS1 (0.73) | CTPS1 | |
| SCHEMBL21077106 | 0.74 | CTPS1 (0.73) | CTPS1 | |
| SCHEMBL21392133 | 0.74 | CTPS1 (0.74) | CTPS1 | |
| SCHEMBL21077270 | 0.73 | CTPS1 (0.51) | CTPS1PTGES | |
| SCHEMBL21076894 | 0.72 | CTPS1 (0.52) | CTPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492454-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2019-06-05 | — | — | EP | disclosed |