Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 16/20 | 0.52 |
| ▸ | CTPS2 | Q9NRF8 | 4/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 3/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21076941 | 0.90 | CTPS1 (0.50) | CTPS1CTPS2 | |
| SCHEMBL21076924 | 0.89 | CTPS1 (0.53) | CTPS1CTPS2 | |
| SCHEMBL21077203 | 0.89 | CTPS1 (0.51) | CTPS1CTPS2ABL1 | |
| SCHEMBL21077063 | 0.89 | CTPS1 (0.49) | CTPS1CTPS2GSK3BDYRK1A | |
| SCHEMBL21077151 | 0.88 | CTPS1 (0.48) | CTPS1CTPS2GSK3BDYRK1A | |
| SCHEMBL21076974 | 0.88 | CTPS1 (0.50) | CTPS1CTPS2 | |
| SCHEMBL21076968 | 0.88 | CTPS1 (0.48) | CTPS1CTPS2 | |
| SCHEMBL21077093 | 0.88 | CTPS1 (0.55) | CTPS1CTPS2ABL1GSK3BDYRK1A | |
| SCHEMBL21077184 | 0.88 | CTPS1 (0.46) | CTPS1CTPS2ABL1 | |
| SCHEMBL21077149 | 0.87 | CTPS1 (0.59) | CTPS1CTPS2ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492454-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2019-06-05 | — | — | EP | disclosed |