Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 16/20 | 0.44 |
| ▸ | CTPS2 | Q9NRF8 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21077133 | 0.85 | CTPS1 (0.53) | CTPS1CTPS2 | |
| SCHEMBL21077258 | 0.84 | CTPS1 (0.45) | CTPS1CTPS2MAPT | |
| SCHEMBL21044249 | 0.83 | CTPS1 (0.66) | CTPS1CTPS2 | |
| SCHEMBL30528941 | 0.83 | CTPS1 (0.66) | CTPS1CTPS2 | |
| SCHEMBL21077160 | 0.83 | CTPS1 (0.54) | CTPS1CTPS2 | |
| SCHEMBL21077255 | 0.82 | CTPS1 (0.46) | CTPS1CTPS2NPC1RAB9AMAPT | |
| SCHEMBL21077191 | 0.82 | CTPS1 (0.47) | CTPS1CTPS2 | |
| SCHEMBL21077142 | 0.81 | CTPS1 (0.49) | CTPS1CTPS2MAPT | |
| SCHEMBL21076994 | 0.80 | CTPS1 (0.48) | CTPS1CTPS2 | |
| SCHEMBL21076933 | 0.80 | CTPS1 (0.46) | CTPS1CTPS2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492454-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2019-06-05 | — | — | EP | disclosed |