Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 12/20 | 0.51 |
| ▸ | CTPS2 | Q9NRF8 | 4/20 | 0.51 |
| ▸ | ABL1 | P00519 | 6/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | FPR1 | P21462 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21077146 | 0.89 | CTPS1 (0.49) | CTPS1CTPS2ABL1 | |
| SCHEMBL21077114 | 0.85 | CTPS1 (0.55) | CTPS1CTPS2 | |
| SCHEMBL21077118 | 0.85 | CTPS1 (0.51) | CTPS1CTPS2ABL1 | |
| SCHEMBL21076872 | 0.84 | CTPS1 (0.52) | CTPS1CTPS2 | |
| SCHEMBL21076994 | 0.84 | CTPS1 (0.48) | CTPS1CTPS2 | |
| SCHEMBL21077207 | 0.83 | CTPS1 (0.69) | CTPS1CTPS2 | |
| SCHEMBL21077142 | 0.83 | CTPS1 (0.49) | CTPS1CTPS2ABL1 | |
| SCHEMBL21077164 | 0.82 | CTPS1 (0.49) | CTPS1CTPS2 | |
| SCHEMBL21077069 | 0.82 | CTPS1 (0.46) | CTPS1CTPS2 | |
| SCHEMBL21044184 | 0.82 | CTPS1 (0.75) | CTPS1CTPS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492454-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2019-06-05 | — | — | EP | disclosed |