Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 11/20 | 0.49 |
| ▸ | CTPS2 | Q9NRF8 | 3/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22762521 | 0.90 | CTPS1 (0.55) | CTPS1CTPS2PIK3CGGSK3BDYRK1A | |
| SCHEMBL21044471 | 0.85 | CTPS1 (0.68) | CTPS1CTPS2 | |
| SCHEMBL30529037 | 0.85 | CTPS1 (0.68) | CTPS1CTPS2 | |
| SCHEMBL21076987 | 0.83 | MAPK1 (0.42) | CTPS1CTPS2MAPK1KMT2ANPC1 | |
| SCHEMBL21077197 | 0.81 | CTPS1 (0.58) | CTPS1CTPS2PIK3CG | |
| SCHEMBL21077073 | 0.80 | CTPS1 (0.48) | CTPS1CTPS2PIK3CGGSK3BDYRK1A | |
| SCHEMBL21044235 | 0.79 | CTPS1 (0.66) | CTPS1CTPS2 | |
| SCHEMBL30528782 | 0.79 | CTPS1 (0.66) | CTPS1CTPS2 | |
| SCHEMBL21077161 | 0.79 | CTPS1 (0.47) | CTPS1CTPS2PIK3CGGSK3BDYRK1A | |
| SCHEMBL21044246 | 0.79 | CTPS1 (0.79) | CTPS1CTPS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492454-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2019-06-05 | — | — | EP | disclosed |