Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 12/20 | 0.53 |
| ▸ | CTPS2 | Q9NRF8 | 2/20 | 0.48 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21077135 | 0.87 | CTPS1 (0.52) | CTPS1CTPS2 | |
| SCHEMBL21387641 | 0.84 | CTPS1 (0.70) | CTPS1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL21044269 | 0.83 | CTPS1 (0.71) | CTPS1CTPS2 | |
| SCHEMBL21077212 | 0.82 | CTPS1 (0.44) | CTPS1CTPS2 | |
| SCHEMBL21077114 | 0.82 | CTPS1 (0.55) | CTPS1CTPS2 | |
| SCHEMBL21076971 | 0.81 | CTPS1 (0.46) | CTPS1CTPS2 | |
| SCHEMBL21076872 | 0.81 | CTPS1 (0.52) | CTPS1CTPS2 | |
| SCHEMBL21076933 | 0.81 | CTPS1 (0.46) | CTPS1CTPS2KDM4E | |
| SCHEMBL21077065 | 0.80 | CTPS1 (0.53) | CTPS1CTPS2 | |
| SCHEMBL21077141 | 0.80 | CTPS1 (0.46) | CTPS1CTPS2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492454-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2019-06-05 | — | — | EP | disclosed |