Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 14/20 | 0.53 |
| ▸ | CTPS2 | Q9NRF8 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21077015 | 0.90 | CTPS1 (0.41) | CTPS1ADRB3PSEN1PSEN2APH1B | |
| SCHEMBL21077047 | 0.90 | CTPS1 (0.52) | CTPS1CTPS2RAB9AMEN1KMT2A | |
| SCHEMBL21077175 | 0.87 | CTPS1 (0.44) | CTPS1CTPS2RAB9AMEN1KMT2A | |
| SCHEMBL21077107 | 0.87 | CTPS1 (0.54) | CTPS1ADRB3 | |
| SCHEMBL21077048 | 0.87 | CTPS1 (0.43) | CTPS1ADRB3 | |
| SCHEMBL21077144 | 0.85 | CTPS1 (0.55) | CTPS1ADRB3 | |
| SCHEMBL21076942 | 0.85 | CTPS1 (0.48) | CTPS1 | |
| SCHEMBL22762461 | 0.84 | CTPS1 (0.55) | CTPS1CTPS2RAB9AMEN1KMT2A | |
| SCHEMBL21077147 | 0.84 | CTPS1 (0.54) | CTPS1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL22491694 | 0.82 | CTPS1 (0.72) | CTPS1CTPS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492454-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2019-06-05 | — | — | EP | disclosed |