Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 12/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | GCK | P35557 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21076992 | 0.88 | CTPS1 (0.40) | CTPS1NTRK1RAB9AGCK | |
| SCHEMBL21077175 | 0.83 | CTPS1 (0.44) | CTPS1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL21077154 | 0.83 | CTPS1 (0.46) | CTPS1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL22491734 | 0.83 | CTPS1 (0.55) | CTPS1 | |
| SCHEMBL21044263 | 0.83 | CTPS1 (0.55) | CTPS1 | |
| SCHEMBL22491626 | 0.83 | CTPS1 (0.55) | CTPS1 | |
| SCHEMBL21077060 | 0.83 | CTPS1 (0.56) | CTPS1 | |
| SCHEMBL21077160 | 0.82 | CTPS1 (0.54) | CTPS1 | |
| SCHEMBL21077216 | 0.81 | CTPS1 (0.49) | CTPS1 | |
| SCHEMBL22762514 | 0.81 | CTPS1 (0.46) | CTPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492454-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2019-06-05 | — | — | EP | disclosed |