Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17867819 | 0.98 | JAK1 (1.00) | JAK1JAK2 | |
| SCHEMBL17868103 | 0.89 | JAK1 (0.84) | JAK1JAK2 | |
| SCHEMBL16565585 | 0.89 | JAK1 (1.00) | JAK1JAK2 | |
| SCHEMBL17868031 | 0.88 | JAK1 (1.00) | JAK1JAK2 | |
| SCHEMBL17868006 | 0.88 | JAK1 (1.00) | JAK1JAK2 | |
| SCHEMBL17868025 | 0.87 | JAK1 (1.00) | JAK1JAK2 | |
| SCHEMBL17867934 | 0.86 | JAK1 (1.00) | JAK1JAK2 | |
| SCHEMBL17867845 | 0.86 | JAK1 (1.00) | JAK1JAK2 | |
| SCHEMBL17867913 | 0.86 | JAK1 (1.00) | JAK1JAK2 | |
| SCHEMBL21078205 | 0.86 | JAK1 (0.81) | JAK1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3041841-B1 | TRIAZOLOPYRIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | HOFFMANN LA ROCHE (CH) | 2019-06-05 | — | — | EP | disclosed |