Bakeprofen

Bakeprofen

SCHEMBL2107798

CC(Oc1cccc(C(=O)c2ccccc2)c1)C(=O)O

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 5/20 0.57
PTGS2 P35354 5/20 0.57
MAPT P10636 2/20 0.57
CXCR1 P25024 2/20 0.57
CXCR2 P25025 2/20 0.57
SMN1; SMN2 Q16637 2/20 0.57
RECQL P46063 1/20 0.57
KDM4E B2RXH2 1/20 0.57
ALDH1A1 P00352 1/20 0.57
LMNA P02545 1/20 0.57
CYP3A4 P08684 1/20 0.57
HPGD P15428 1/20 0.57
MAPK1 P28482 1/20 0.57
PMP22 Q01453 1/20 0.57
SLC22A6 Q4U2R8 1/20 0.57
HSD17B10 Q99714 1/20 0.57
CXCL8 P10145 1/20 0.57
THPO P40225 1/20 0.57
HIF1A Q16665 1/20 0.57
CYP1A2 P05177 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11303352 0.91 TDP1 (0.50) PTGS1PTGS2MAPTCXCR1CXCR2
SCHEMBL14446354 0.86 ATM (0.59) PTGS1PTGS2MAPTCXCR1CXCR2
SCHEMBL12852977 0.86 CYP1A2 (0.69) MAPTSMN1; SMN2ALDH1A1LMNAHPGD
SCHEMBL15329830 0.85 MAOB (0.54) MAPTALDH1A1CYP1A2GAACYP2C9
SCHEMBL11411964 0.84 SRD5A2 (0.57) MAPTALDH1A1LMNACYP3A4HSD17B10
SCHEMBL320845 0.82 TSHR (0.52) SMN1; SMN2ALDH1A1HPGDMAPK1CYP1A2
SCHEMBL8088796 0.82 GAA (0.50) SMN1; SMN2ALDH1A1LMNACYP1A2GAA
SCHEMBL321520 0.82 TSHR (0.52) SMN1; SMN2ALDH1A1HPGDMAPK1CYP1A2
SCHEMBL127395 0.82 CYP1A2 (0.78) HPGDCYP1A2GAACYP2C9PKM
SCHEMBL43054 0.82 CYP1A2 (0.78) HPGDCYP1A2GAACYP2C9PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
EP-1336602-A1 Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases Scaramuzzino, Giovanni (IT) 2003-08-20 EP claimed
US-4277497-A AND SALTS WITH AMINO ACIDS UNICLER (FR) 1981-07-07 US claimed
US-4242358-A M-BENZOYL-PHENOXYALKYLCARBOXYLIC ACIDS SOCIETE DE RECHERCHES INDUSTRIELLES (SORI) (FR) 1980-12-30 US claimed
US-20220047505-A1 Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration STI PHARMA, LLC (US) 2022-02-17 US disclosed
US-11191719-B2 Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration STI PHARMA, LLC (US) 2021-12-07 US disclosed
US-10463611-B2 Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration STI PHARMA, LLC (US) 2019-11-05 US disclosed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US disclosed
US-20140154313-A1 Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration STI PHARMA, LLC (US) 2014-06-05 US disclosed
EP-2717860-A1 CONTROLLED ABSORPTION WATER-SOLUBLE PHARMACEUTICALLY ACTIVE ORGANIC COMPOUND FORMULATION FOR ONCE-DAILY ADMINISTRATION STI Pharma, LLC (US) 2014-04-16 EP disclosed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP disclosed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO disclosed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US disclosed
EP-1336602-A1 Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases Scaramuzzino, Giovanni (IT) 2003-08-20 EP disclosed
US-4277497-A AND SALTS WITH AMINO ACIDS UNICLER (FR) 1981-07-07 US disclosed
US-4277497-A AND SALTS WITH AMINO ACIDS UNICLER (FR) 1981-07-07 US disclosed