Cinoxopazide

Cinoxopazide

SCHEMBL2107817

O=C(/C=C/c1ccc2c(c1)OCO2)N1CCN(CC(=O)N2CCCC2)CC1

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.78
NPC1 O15118 4/20 0.76
RAB9A P51151 4/20 0.76
TRPV1 Q8NER1 3/20 0.76
KDM4E B2RXH2 8/20 0.72
ALDH1A1 P00352 7/20 0.72
MEN1 O00255 3/20 0.72
KMT2A Q03164 3/20 0.72
HPGD P15428 5/20 0.68
SMN1; SMN2 Q16637 3/20 0.68
CYP3A4 P08684 3/20 0.68
HSD17B10 Q99714 2/20 0.68
LMNA P02545 2/20 0.68
CYP1A2 P05177 2/20 0.68
CYP2D6 P10635 2/20 0.68
CTSD P07339 1/20 0.68
ABCB1 P08183 1/20 0.68
ALOX5 P09917 1/20 0.68
GABRA1 P14867 1/20 0.68
MAOA P21397 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cinoxopazide SCHEMBL10520206 1.00 MAOB (0.78) MAOBNPC1RAB9ATRPV1KDM4E
SCHEMBL3767741 0.89 KDM4E (0.63) MAOBNPC1RAB9ATRPV1KDM4E
SCHEMBL3767737 0.89 KDM4E (0.63) MAOBNPC1RAB9ATRPV1KDM4E
SCHEMBL3115704 0.88 MAOB (1.00) MAOBNPC1RAB9ATRPV1KDM4E
SCHEMBL3115705 0.88 MAOB (1.00) MAOBNPC1RAB9ATRPV1KDM4E
Ilepcimide SCHEMBL30887538 0.87 NPC1 (1.00) MAOBNPC1RAB9ATRPV1KDM4E
Ilepcimide SCHEMBL29738474 0.87 NPC1 (1.00) MAOBNPC1RAB9ATRPV1KDM4E
Ilepcimide SCHEMBL3838030 0.87 NPC1 (1.00) MAOBNPC1RAB9ATRPV1KDM4E
Ilepcimide SCHEMBL668328 0.87 NPC1 (1.00) MAOBNPC1RAB9ATRPV1KDM4E
Ilepcimide SCHEMBL30237912 0.87 NPC1 (1.00) MAOBNPC1RAB9ATRPV1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-20220047505-A1 Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration STI PHARMA, LLC (US) 2022-02-17 US disclosed
US-11191719-B2 Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration STI PHARMA, LLC (US) 2021-12-07 US disclosed
US-10463611-B2 Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration STI PHARMA, LLC (US) 2019-11-05 US disclosed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US disclosed
US-20140154313-A1 Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration STI PHARMA, LLC (US) 2014-06-05 US disclosed
EP-2717860-A1 CONTROLLED ABSORPTION WATER-SOLUBLE PHARMACEUTICALLY ACTIVE ORGANIC COMPOUND FORMULATION FOR ONCE-DAILY ADMINISTRATION STI Pharma, LLC (US) 2014-04-16 EP disclosed
WO-2012170676-A1 CONTROLLED ABSORPTION WATER-SOLUBLE PHARMACEUTICALLY ACTIVE ORGANIC COMPOUND FORMULATION FOR ONCE-DAILY ADMINISTRATION STI PHARMA, LLC (US) 2012-12-13 WO disclosed
US-7905852-B2 Skin-contacting-adhesive free dressing JENNINGS-SPRING BARBARA 2011-03-15 US disclosed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US disclosed
WO-2010024870-A1 SKIN-CONTACTING-ADHESIVE FREE DRESSING JENNINGS-SPRING BARBARA BROOKE (US) 2010-03-04 WO disclosed
US-20090005722-A1 Skin-contacting-adhesive free dressing JENNLNGS-SPRING BARBARA 2009-01-01 US disclosed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP disclosed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO disclosed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US disclosed
US-4808582-A LEARNING ENHANCEMENT DELALANDE S.A. (FR) 1989-02-28 US disclosed