Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16554446 | 0.80 | JAK2 (1.00) | JAK1JAK2 | |
| Trifluoroacetic Acid SCHEMBL16553967 | 0.77 | JAK1 (0.62) | JAK1JAK2 | |
| SCHEMBL2640328 | 0.76 | JAK2 (0.65) | JAK1JAK2 | |
| SCHEMBL16553969 | 0.76 | JAK1 (0.60) | JAK1JAK2 | |
| SCHEMBL21078204 | 0.75 | JAK1 (0.71) | JAK1JAK2 | |
| SCHEMBL16565863 | 0.74 | JAK2 (0.75) | JAK1JAK2 | |
| SCHEMBL16565336 | 0.73 | JAK1 (0.72) | JAK1JAK2 | |
| SCHEMBL16565647 | 0.72 | JAK2 (0.77) | JAK1JAK2 | |
| SCHEMBL17868075 | 0.71 | JAK1 (0.86) | JAK1JAK2 | |
| SCHEMBL21078051 | 0.71 | JAK1 (0.74) | JAK1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3041841-B1 | TRIAZOLOPYRIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | HOFFMANN LA ROCHE (CH) | 2019-06-05 | — | — | EP | disclosed |