Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17888362 | 0.82 | NAMPT (0.39) | NAMPT | |
| SCHEMBL21078319 | 0.78 | NAMPT (0.37) | NAMPT | |
| SCHEMBL19226446 | 0.78 | NAMPT (0.37) | NAMPT | |
| SCHEMBL15100048 | 0.77 | NAMPT (0.37) | NAMPT | |
| SCHEMBL6783552 | 0.77 | NAMPT (0.37) | NAMPT | |
| SCHEMBL21077897 | 0.76 | NAMPT (0.34) | NAMPT | |
| SCHEMBL19226447 | 0.74 | NAMPT (0.35) | NAMPT | |
| SCHEMBL19499473 | 0.71 | NAMPT (0.32) | NAMPT | |
| SCHEMBL19226566 | 0.67 | NAMPT (0.63) | NAMPT | |
| SCHEMBL10153335 | 0.67 | GBA1 (0.49) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3041841-B1 | TRIAZOLOPYRIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | HOFFMANN LA ROCHE (CH) | 2019-06-05 | — | — | EP | disclosed |