SCHEMBL2107934

SCHEMBL2107934

O=C1CCC(c2ccccc2)C(=O)N1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 19/20 1.00
DDB1 Q16531 18/20 1.00
POLB P06746 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31704153 1.00 CRBN (1.00) CRBNDDB1POLB
SCHEMBL31704110 1.00 CRBN (1.00) CRBNDDB1POLB
SCHEMBL19370870 0.90 CRBN (0.81) CRBNDDB1POLB
SCHEMBL7828080 0.81 CRBN (0.70) CRBNDDB1POLB
SCHEMBL7827796 0.81 CRBN (0.70) CRBNDDB1POLB
SCHEMBL25026926 0.81 CRBN (0.70) CRBNDDB1POLB
SCHEMBL1553566 0.81 CRBN (1.00) CRBNDDB1POLB
SCHEMBL19586225 0.81 CRBN (1.00) CRBNDDB1POLB
SCHEMBL8182409 0.81 CRBN (0.70) CRBNDDB1POLB
SCHEMBL25026923 0.81 CRBN (0.70) CRBNDDB1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137677-A1 PROTACS USEFUL AGAINST THE MAIN PROTEASE SARS-COV-2 TOCRIS COOKSON LTD (GB) 2026-05-21 US claimed
EP-4673438-A1 PROTEOLYSIS-TARGETING CHIMERAS Tocris Cookson Limited (GB) 2026-01-07 EP claimed
EP-4598582-A1 PROTEOLYSIS-TARGETING CHIMERAS AGAINST THE PAPAIN-LIKE PROTEASE OF SARS-COV-2 Tocris Cookson Limited (GB) 2025-08-13 EP claimed
EP-4598914-A1 PROTACS USEFUL AGAINST THE MAIN PROTEASE SARS-COV-2 Tocris Cookson Limited (GB) 2025-08-13 EP claimed
WO-2024238872-A2 ISOINDOLINONE-GLUTARIMIDE ANTIBODY CONJUGATES, AND USES THEREOF FIREFLY BIO, INC. (US) 2024-11-21 WO claimed
WO-2024222726-A1 DEGRADATION AGENT FOR CYCLIN-DEPENDENT KINASE (CDK) 12/13, COMPOSITION AND USE THEREOF 浙江大学 2024-10-31 WO claimed
WO-2024180157-A1 PROTEOLYSIS-TARGETING CHIMERAS TOCRIS COOKSON LIMITED (GB) 2024-09-06 WO claimed
WO-2024074848-A1 PROTACS USEFUL AGAINST THE MAIN PROTEASE SARS-COV-2 TOCRIS COOKSON LIMITED (GB) 2024-04-11 WO claimed
WO-2024074849-A1 PROTEOLYSIS-TARGETING CHIMERAS AGAINST THE PAPAIN-LIKE PROTEASE OF SARS-COV-2 TOCRIS COOKSON LIMITED (GB) 2024-04-11 WO claimed
CN-116675731-A Small molecule conjugate of targeted cyclin-dependent kinase 12/13 and application thereof 浙江大学 2023-09-01 CN claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-20260137677-A1 PROTACS USEFUL AGAINST THE MAIN PROTEASE SARS-COV-2 TOCRIS COOKSON LTD (GB) 2026-05-21 US disclosed
US-12605450-B2 C3-carbon linked glutarimide Degronimers for target protein degradation C4 THERAPEUTICS, INC. (US) 2026-04-21 US disclosed
EP-0888304-B1 SUBSTITUTED 3-ARYL-3-CARBOXYALKYL GLUTARAMIDES, METHOD FOR PREPARING SAME BY 4-ARYLO-4-CYANOHEPTANE DICARBOXYLIC ACID CYCLISATION, AND USE THEREOF FOR PREPARING 3-ARYL-3-HYDROXYALKYLPIPERIDINES SANOFI SYNTHELABO (FR) 2001-10-04 EP disclosed
EP-0417143-A1 CYCLIC LACTAMS FOR CHOLESTEROL AND ATHEROSCLEROSIS CONTROL THE UPJOHN COMPANY (US) 1991-03-20 EP disclosed
WO-1989011856-A2 CYCLIC LACTAMS FOR CHOLESTEROL AND ATHEROSCLEROSIS CONTROL THE UPJOHN COMPANY (US) 1989-12-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12605450-B2 C3-carbon linked glutarimide Degronimers for target protein degradation NEDD4, UBE3A, UBE3C CRBN 11/4885DDB1 279/4885POLB 4356/4885
US-20260137677-A1 PROTACS USEFUL AGAINST THE MAIN PROTEASE SARS-COV-2 XIAP, MDM2, SARS1 CRBN 4/4885DDB1 429/4885POLB 2039/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.