⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21046317 | 0.94 | — | — | |
| SCHEMBL21046318 | 0.94 | — | — | |
| SCHEMBL19534314 | 0.94 | — | — | |
| SCHEMBL21082142 | 0.92 | — | — | |
| SCHEMBL21082130 | 0.91 | — | — | |
| SCHEMBL21082126 | 0.91 | — | — | |
| SCHEMBL21082144 | 0.91 | — | — | |
| SCHEMBL21082091 | 0.91 | — | — | |
| SCHEMBL19520715 | 0.90 | — | — | |
| SCHEMBL19520712 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210206715-A1 | Benzoylglycine Derivatives and Methods of Making and Using Same | DUKE UNIVERSITY (US) | 2021-07-08 | — | — | US | disclosed |
| US-11034649-B2 | Benzoylglycine derivatives and methods of making and using same | DUKE UNIVERSITY (US) | 2021-06-15 | — | — | US | disclosed |
| US-10550074-B2 | Benzoylglycine derivatives and methods of making and using same | DUKE UNIVERSITY (US) | 2020-02-04 | — | — | US | disclosed |
| US-20190169114-A1 | Benzoylglycine Derivatives and Methods of Making and Using Same | DUKE UNIVERSITY | 2019-06-06 | — | — | US | disclosed |