Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.51 |
| ▸ | DGAT1 | O75907 | 7/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21087317 | 0.96 | GLP1R (0.55) | GLP1RFOLH1DGAT1 | |
| SCHEMBL21087028 | 0.90 | GLP1R (0.56) | GLP1RFOLH1DGAT1 | |
| SCHEMBL21087318 | 0.89 | GLP1R (0.55) | GLP1RFOLH1DGAT1 | |
| SCHEMBL21087314 | 0.85 | GLP1R (0.61) | GLP1RFOLH1DGAT1 | |
| SCHEMBL21087448 | 0.77 | GLP1R (0.52) | GLP1RFOLH1DGAT1 | |
| SCHEMBL23900363 | 0.77 | FOLH1 (0.54) | FOLH1DGAT1 | |
| SCHEMBL16983523 | 0.77 | FOLH1 (0.51) | GLP1RFOLH1DGAT1 | |
| SCHEMBL19216011 | 0.77 | FOLH1 (0.51) | GLP1RFOLH1DGAT1 | |
| SCHEMBL18475519 | 0.75 | FOLH1 (0.50) | GLP1RFOLH1DGAT1 | |
| SCHEMBL19216012 | 0.75 | FOLH1 (0.50) | GLP1RFOLH1DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190175744-A1 | INSULIN-INCRETIN CONJUGATES | MERCK SHARP & DOHME CORP. (US) | 2019-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190175744-A1 | INSULIN-INCRETIN CONJUGATES | GIPR, GLP1R, GCGR | GLP1R 2/4885FOLH1 320/4885DGAT1 315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.