⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL71473 | 1.00 | — | — | |
| SCHEMBL66151 | 1.00 | — | — | |
| SCHEMBL74513 | 1.00 | — | — | |
| SCHEMBL66150 | 1.00 | — | — | |
| SCHEMBL9267031 | 1.00 | CHRNA7 (0.48) | — | |
| SCHEMBL1039747 | 1.00 | — | — | |
| SCHEMBL1404039 | 0.97 | CHRNA7 (0.46) | — | |
| Hydrochloric Acid SCHEMBL731086 | 0.97 | CHRNA7 (0.46) | — | |
| SCHEMBL8712522 | 0.97 | CHRNA7 (0.46) | — | |
| Hydrochloric Acid SCHEMBL1191218 | 0.97 | CHRNA7 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200308168-A1 | FLUOROPHENYL SUBSTITUTED MUSCARINIC RECEPTOR LIGANDS WITH SELECTIVITY FOR M3 OVER M2 | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2020-10-01 | — | — | US | disclosed |
| WO-2019110521-A1 | FLUOROPHENYL SUBSTITUTED MUSCARINIC RECEPTOR LIGANDS WITH SELECTIVITY FOR M3 OVER M2 | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2019-06-13 | — | — | WO | disclosed |