Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | KDM1A | O60341 | 9/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15033023 | 0.85 | KDM4E (0.50) | KDM4EKDM1AMEN1KMT2ADRD4 | |
| SCHEMBL28175300 | 0.85 | KDM4E (0.50) | KDM4EKDM1AMEN1KMT2ADRD4 | |
| SCHEMBL17963504 | 0.84 | KDM4E (0.65) | KDM4EKDM1AMEN1KMT2A | |
| SCHEMBL20843153 | 0.84 | KDM1A (0.53) | KDM4EKDM1AMEN1KMT2ADRD4 | |
| SCHEMBL12814152 | 0.84 | KDM1A (0.53) | KDM4EKDM1ADRD4 | |
| SCHEMBL17963554 | 0.84 | KDM4E (0.55) | KDM4EKDM1ADRD4SIRT2SIRT1 | |
| SCHEMBL20843175 | 0.83 | KDM1A (0.58) | KDM4EKDM1ADRD4 | |
| SCHEMBL20843229 | 0.82 | KDM1A (0.52) | KDM4EKDM1ADRD4SIRT2SIRT1 | |
| SCHEMBL12813914 | 0.82 | KDM4E (0.48) | KDM4EKDM1AMEN1KMT2ADRD4 | |
| SCHEMBL17987974 | 0.82 | KDM1A (0.52) | KDM4EKDM1ADRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3286172-B1 | LSD1 INHIBITORS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS INC (US) | 2019-06-12 | — | — | EP | disclosed |