Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | AKT1 | P31749 | 2/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.41 |
| ▸ | GLS | O94925 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8017533 | 0.92 | HTR2C (0.47) | HTR2CSLC6A4AKT1RIPK1GLS | |
| SCHEMBL18173003 | 0.86 | AKT1 (0.43) | HTR2CSLC6A4AKT1RIPK1CYP1A2 | |
| SCHEMBL15261600 | 0.84 | HTR2C (0.43) | HTR2CSLC6A4AKT1RIPK1CYP1A2 | |
| SCHEMBL7408449 | 0.84 | HTR2C (0.43) | HTR2CSLC6A4AKT1RIPK1GLS | |
| SCHEMBL29430479 | 0.83 | HTR2C (0.45) | HTR2CSLC6A4AKT1RIPK1GLS | |
| SCHEMBL11470297 | 0.83 | HTR2C (0.45) | HTR2CSLC6A4AKT1RIPK1GLS | |
| SCHEMBL30264826 | 0.83 | HSP90AA1 (0.47) | HTR2CSLC6A4RIPK1GLSPDK2 | |
| SCHEMBL22687996 | 0.82 | HTR2C (0.44) | HTR2CSLC6A4AKT1RIPK1GLS | |
| SCHEMBL1399434 | 0.81 | HTR2C (0.43) | HTR2CSLC6A4AKT1RIPK1GLS | |
| SCHEMBL2061803 | 0.81 | SLC6A4 (0.43) | HTR2CSLC6A4AKT1RIPK1GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3286172-B1 | LSD1 INHIBITORS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS INC (US) | 2019-06-12 | — | — | EP | disclosed |