SCHEMBL21089412

SCHEMBL21089412

CC1CN(C(=O)c2ccccc2-c2ccc(-c3cnc(N)cn3)c(F)c2)CC(C)N1

nearest known ligand 0.80

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 20/20 0.80
FEN1 P39748 20/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15916181 0.89 FEN1 (1.00) ALOX5APFEN1
SCHEMBL15917135 0.88 ALOX5AP (1.00) ALOX5APFEN1
SCHEMBL15915742 0.85 FEN1 (0.77) ALOX5APFEN1
SCHEMBL15916797 0.84 ALOX5AP (0.82) ALOX5APFEN1
SCHEMBL20627179 0.84 FEN1 (0.81) ALOX5APFEN1
SCHEMBL15916255 0.83 ALOX5AP (0.77) ALOX5APFEN1
SCHEMBL20627073 0.83 FEN1 (0.80) ALOX5APFEN1
SCHEMBL17362341 0.83 FEN1 (0.80) ALOX5APFEN1
SCHEMBL20627184 0.83 ALOX5AP (1.00) ALOX5APFEN1
SCHEMBL15918380 0.83 ALOX5AP (1.00) ALOX5APFEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3495359-A1 FLAP MODULATORS Janssen Pharmaceutica NV (BE) 2019-06-12 EP disclosed