Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP51A1 | Q16850 | 12/20 | 0.71 |
| ▸ | PYGL | P06737 | 5/20 | 0.71 |
| ▸ | PYGM | P11217 | 1/20 | 0.71 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | UGCG | Q16739 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2606918 | 1.00 | CYP51A1 (0.71) | CYP51A1PYGLPYGMHRH4CYP3A4 | |
| SCHEMBL2606915 | 1.00 | CYP51A1 (0.71) | CYP51A1PYGLPYGMHRH4CYP3A4 | |
| SCHEMBL2606914 | 0.95 | CYP51A1 (0.64) | CYP51A1PYGLPYGMHRH4 | |
| SCHEMBL2107376 | 0.95 | CYP51A1 (0.78) | CYP51A1PYGLPYGMHRH4CYP3A4 | |
| SCHEMBL13271494 | 0.88 | CYP51A1 (0.59) | CYP51A1PYGLPYGMHRH4 | |
| SCHEMBL2106974 | 0.88 | CYP51A1 (0.70) | CYP51A1PYGLPYGM | |
| SCHEMBL2107356 | 0.88 | CYP51A1 (0.67) | CYP51A1PYGLPYGM | |
| SCHEMBL2106891 | 0.86 | CYP51A1 (0.65) | CYP51A1PYGLPYGMHRH4CYP3A4 | |
| SCHEMBL2606793 | 0.86 | CYP51A1 (0.65) | CYP51A1PYGLPYGMHRH4CYP3A4 | |
| SCHEMBL13271504 | 0.86 | CYP51A1 (0.65) | CYP51A1PYGLPYGMHRH4CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158622-B2 | Pyrrolopyridine-2-carboxylic acid amide inhibitors of glycogen phosphorylase | PROSIDION LIMITED (GB) | 2012-04-17 | — | — | US | disclosed |