Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 4/20 | 0.39 |
| ▸ | RXRA | P19793 | 3/20 | 0.39 |
| ▸ | RXRG | P48443 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21091907 | 1.00 | KMT2A (0.51) | KMT2AMAOAMAOBHTR1ASLC6A2 | |
| SCHEMBL11726141 | 0.82 | KMT2A (0.47) | KMT2AMAOAMAOBHTR1ASLC6A2 | |
| SCHEMBL11668594 | 0.81 | KDM1A (0.45) | MAOAMAOBHTR1ASLC6A2SLC6A4 | |
| SCHEMBL22681383 | 0.81 | KDM1A (0.45) | MAOAMAOBHTR1ASLC6A2SLC6A4 | |
| SCHEMBL11668598 | 0.81 | KDM1A (0.45) | MAOAMAOBHTR1ASLC6A2SLC6A4 | |
| SCHEMBL22657347 | 0.81 | KDM1A (0.45) | MAOAMAOBHTR1ASLC6A2SLC6A4 | |
| SCHEMBL22657349 | 0.81 | KDM1A (0.45) | MAOAMAOBHTR1ASLC6A2SLC6A4 | |
| SCHEMBL11668589 | 0.81 | KDM1A (0.45) | MAOAMAOBHTR1ASLC6A2SLC6A4 | |
| SCHEMBL10892232 | 0.80 | KMT2A (0.45) | KMT2AMAOAMAOBLIPGRXRB | |
| SCHEMBL1746528 | 0.78 | MAOB (0.58) | KMT2AMAOAMAOBHTR1ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019112913-A1 | BETA-2 SELECTIVE ADRENERGIC RECEPTOR AGONISTS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2019-06-13 | — | — | WO | disclosed |