Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.44 |
| ▸ | PDE5A | O76074 | 2/20 | 0.43 |
| ▸ | ACP1 | P24666 | 2/20 | 0.43 |
| ▸ | OGG1 | O15527 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5800694 | 1.00 | KDM4E (0.55) | KDM4EGAAMAPTHSD17B10LRRK2 | |
| SCHEMBL5778944 | 1.00 | KDM4E (0.55) | KDM4EGAAMAPTHSD17B10LRRK2 | |
| SCHEMBL19851082 | 1.00 | KDM4E (0.55) | KDM4EGAAMAPTHSD17B10LRRK2 | |
| SCHEMBL5775863 | 1.00 | KDM4E (0.55) | KDM4EGAAMAPTHSD17B10LRRK2 | |
| Hydrochloric Acid SCHEMBL11561576 | 0.98 | KDM4E (0.53) | KDM4EGAAMAPTHSD17B10LRRK2 | |
| SCHEMBL15965809 | 0.98 | KDM4E (0.52) | KDM4EGAAMAPTHSD17B10LRRK2 | |
| SCHEMBL5958267 | 0.91 | UTS2R (0.43) | KDM4EGAAMAPTHSD17B10LRRK2 | |
| SCHEMBL26349385 | 0.83 | HRH3 (0.51) | KDM4EMAPTHSD17B10LMNAKMT2A | |
| SCHEMBL13351533 | 0.81 | BRD4 (0.47) | GAASMN1; SMN2 | |
| SCHEMBL23954467 | 0.79 | KDM4E (0.64) | KDM4EGAAMAPTHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3495362-A1 | IMIDAZOPYRIDINE THIOGLYCOLIC ACID DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shandong University (CN) | 2019-06-12 | — | — | EP | disclosed |