⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2199290 | 0.82 | — | — | |
| SCHEMBL20520963 | 0.77 | — | — | |
| SCHEMBL3152779 | 0.76 | — | — | |
| SCHEMBL271887 | 0.76 | — | — | |
| SCHEMBL22608840 | 0.76 | — | — | |
| SCHEMBL20520815 | 0.76 | — | — | |
| SCHEMBL4722016 | 0.73 | — | — | |
| SCHEMBL3143810 | 0.73 | — | — | |
| SCHEMBL1984014 | 0.71 | — | — | |
| SCHEMBL16877108 | 0.71 | GBA1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117083286-A | Pair A 2A A is a 3 Adenosine derivatives having antagonism to adenosine receptor and process for preparing same | 未来制药有限公司 | 2023-11-17 | — | — | CN | claimed |
| EP-3710439-B1 | KRAS G12C INHIBITORS | MIRATI THERAPEUTICS INC (US) | 2023-02-15 | — | — | EP | claimed |
| CN-114716343-A | Novel NAMPT enzyme agonist, preparation and application thereof | 清华大学 | 2022-07-08 | — | — | CN | claimed |
| CN-111989321-A | KRAS G12C inhibitors | 米拉蒂治疗股份有限公司 | 2020-11-24 | — | — | CN | claimed |
| EP-3710439-A1 | KRAS G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2020-09-23 | — | — | EP | claimed |
| US-20200181103-A1 | DERIVATIVES OF SOBETIROME | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2020-06-11 | — | — | US | claimed |
| EP-3478680-B1 | NOVEL TETRAHYDROPYRIDOPYRIMIDINES FOR THE TREATMENT AND PROPHYLAXIS OF HBV INFECTION | HOFFMANN LA ROCHE (CH) | 2020-04-22 | — | — | EP | claimed |
| CN-111004107-A | Substituted dichlorobenzene compound containing propenone, preparation method and application | 山东大学 | 2020-04-14 | — | — | CN | claimed |
| US-10392356-B2 | Derivatives of sobetirome | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2019-08-27 | — | — | US | claimed |
| US-20190241559-A1 | NOVEL TETRAHYDROPYRIDOPYRIMIDINES FOR THE TREATMENT AND PROPHYLAXIS OF HBV INFECTION | HOFFMANN-LA ROCHE INC. (US) | 2019-08-08 | — | — | US | claimed |
| EP-1658263-B1 | NOVEL AMINOBENZOPHENONE COMPOUNDS | LEO PHARMA AS (DK) | 2010-06-02 | — | — | EP | claimed |
| JP-2006528597-A | — | — | 2006-12-21 | — | — | JP | claimed |
| US-20060166990-A1 | Novel aminobenzophenone compounds | LEO PHARMA A/S (DK) | 2006-07-27 | — | — | US | claimed |
| EP-1658263-A1 | NOVEL AMINOBENZOPHENONE COMPOUNDS | Leo Pharma A/S (DK) | 2006-05-24 | — | — | EP | claimed |
| EP-1341412-B1 | INDOLOCARBAZOLE ANTICANCER AGENTS AND METHODS OF USING THEM | ADVANCED LIFE SCIENCES INC (US) | 2006-01-11 | — | — | EP | claimed |
| WO-2005009940-A1 | NOVEL AMINOBENZOPHENONE COMPOUNDS | LEO PHARMA A/S (DK) | 2005-02-03 | — | — | WO | claimed |
| EP-1341412-A1 | INDOLOCARBAZOLE ANTICANCER AGENTS AND METHODS OF USING THEM | Advanced Life Sciences, Inc. (US) | 2003-09-10 | — | — | EP | claimed |
| US-6605596-B2 | Topoisomerase I inhibitors | ADVANCED LIFE SCIENCES, INC. | 2003-08-12 | — | — | US | claimed |
| US-20030087842-A1 | Indolocarbazole anticancer agents and methods of using them | ADVANCED LIFE SCIENCES, INC. | 2003-05-08 | — | — | US | claimed |
| WO-2002048166-A1 | INDOLOCARBAZOLE ANTICANCER AGENTS AND METHODS OF USING THEM | ADVANCED LIFE SCIENCES, INC. (US) | 2002-06-20 | — | — | WO | claimed |