Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12603985 | 0.88 | IDO1 (0.81) | IDO1KMT2ALMNATDP1MEN1 | |
| SCHEMBL18071737 | 0.81 | KMT2A (0.56) | IDO1KMT2ALMNATDP1MEN1 | |
| SCHEMBL13671720 | 0.80 | KDM4E (0.60) | KMT2ALMNATDP1MEN1ALDH1A1 | |
| SCHEMBL9513662 | 0.80 | KDM4E (0.56) | IDO1KMT2ALMNATDP1MEN1 | |
| SCHEMBL12968129 | 0.80 | KDM4E (0.60) | KMT2ALMNATDP1MEN1ALDH1A1 | |
| SCHEMBL30498761 | 0.80 | IDO1 (0.68) | IDO1KMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL7108654 | 0.80 | IDO1 (0.68) | IDO1KMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL10337826 | 0.79 | IDO1 (0.68) | IDO1KMT2ALMNATDP1ALDH1A1 | |
| SCHEMBL7072839 | 0.79 | IDO1 (0.68) | IDO1LMNAALDH1A1GPR84CYP1A2 | |
| SCHEMBL12599103 | 0.79 | IDO1 (1.00) | IDO1KMT2ALMNAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190183812-A1 | Compounds For The Treatment Of Neuromuscular Disorders | NMD PHARMA A/S (DK) | 2019-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190183812-A1 | Compounds For The Treatment Of Neuromuscular Disorders | RYR1, CACNB1, RYR2 | IDO1 2007/4885KMT2A 3390/4885LMNA 2204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.