Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 19/20 | 0.83 |
| ▸ | MTOR | P42345 | 10/20 | 0.67 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.65 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.65 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.65 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.65 |
| ▸ | PRKDC | P78527 | 1/20 | 0.65 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.65 |
| ▸ | RICTOR | Q6R327 | 1/20 | 0.65 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.65 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.65 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.65 |
| ▸ | MAPKAP1 | Q9BPZ7 | 1/20 | 0.65 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.65 |
| ▸ | IRAK3 | Q9Y616 | 1/20 | 0.65 |
| ▸ | PI4KA | P42356 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30572664 | 1.00 | PIK3CA (0.83) | PIK3CAMTORPIK3CGPIK3CDPIK3CB | |
| SCHEMBL30572744 | 1.00 | PIK3CA (0.83) | PIK3CAMTORPIK3CGPIK3CDPIK3CB | |
| Trifluoroacetic Acid SCHEMBL25389742 | 0.94 | PIK3CA (0.74) | PIK3CAMTORPIK3CGPIK3CDPIK3CB | |
| Trifluoroacetic Acid SCHEMBL30572720 | 0.94 | PIK3CA (0.74) | PIK3CAMTORPIK3CGPIK3CDPIK3CB | |
| SCHEMBL17833771 | 0.93 | PIK3CA (0.87) | PIK3CAMTORPIK3CGPIK3CDPIK3CB | |
| SCHEMBL21096831 | 0.91 | PIK3CA (0.84) | PIK3CAMTORPIK3CGPIK3CDPIK3CB | |
| SCHEMBL25388029 | 0.91 | PIK3CA (0.69) | PIK3CAMTORPIK3CGPIK3CDPIK3CB | |
| SCHEMBL17060463 | 0.91 | PIK3CA (1.00) | PIK3CAMTORPIK3CGPIK3CDPIK3CB | |
| SCHEMBL25391837 | 0.91 | PIK3CA (0.68) | PIK3CAMTORPIK3CGPIK3CDPIK3CB | |
| SCHEMBL30572732 | 0.90 | PIK3CA (0.68) | PIK3CAMTORPIK3CGPIK3CDPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210000966-A1 | HSP90-TARGETING CONJUGATES AND FORMULATIONS THEREOF | TVA (ABC), LLC | 2021-01-07 | — | — | US | disclosed |
| WO-2019118830-A1 | HSP90-TARGETING CONJUGATES AND FORMULATIONS THEREOF | TARVEDA THERAPEUTICS, INC. (US) | 2019-06-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210000966-A1 | HSP90-TARGETING CONJUGATES AND FORMULATIONS THEREOF | HSP90AB1, HSP90AA1, HSP90B1 | PIK3CA 3406/4885MTOR 2636/4885PIK3CG 3503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.