Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 11/20 | 0.75 |
| ▸ | PIK3CG | P48736 | 10/20 | 0.75 |
| ▸ | PI4KB | Q9UBF8 | 7/20 | 0.75 |
| ▸ | PIK3C3 | Q8NEB9 | 4/20 | 0.75 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.75 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.75 |
| ▸ | PIK3C2A | O00443 | 1/20 | 0.75 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.75 |
| ▸ | PI4KA | P42356 | 1/20 | 0.75 |
| ▸ | PRKDC | P78527 | 1/20 | 0.75 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29373332 | 0.86 | PIK3CD (1.00) | PIK3CDPIK3CGPI4KBPIK3C3PIK3CA | |
| SCHEMBL48649 | 0.86 | PIK3CD (1.00) | PIK3CDPIK3CGPI4KBPIK3C3PIK3CA | |
| SCHEMBL2396076 | 0.83 | PIK3CD (0.72) | PIK3CDPIK3CGPI4KBPIK3C3PIK3CA | |
| SCHEMBL2397554 | 0.83 | PIK3CD (0.70) | PIK3CDPIK3CGPI4KBPIK3C3PIK3CA | |
| SCHEMBL2400053 | 0.81 | PIK3CD (0.68) | PIK3CDPIK3CGPI4KBPIK3C3PIK3CA | |
| SCHEMBL2396778 | 0.81 | PIK3CD (0.68) | PIK3CDPIK3CGPI4KBPIK3C3PIK3CA | |
| SCHEMBL2396759 | 0.81 | PIK3CD (0.67) | PIK3CDPIK3CGPI4KBPIK3C3PIK3CA | |
| SCHEMBL2393804 | 0.81 | PIK3CD (0.67) | PIK3CDPIK3CGPI4KBPIK3C3PIK3CA | |
| SCHEMBL48625 | 0.74 | PIK3CD (0.67) | PIK3CDPIK3CGPI4KBPIK3C3PIK3CA | |
| SCHEMBL14851735 | 0.74 | PIK3CD (0.77) | PIK3CDPIK3CGPI4KBPIK3C3PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021202830-A2 | HSP90-BINDING CONJUGATES AND FORMULATIONS THEREOF | TARVEDA THERAPEUTICS, INC. (US) | 2021-10-07 | — | — | WO | disclosed |
| WO-2020146657-A1 | PI4-KINASE INHIBITORS WITH ANTI-CANCER ACTIVITY | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2020-07-16 | — | — | WO | disclosed |
| WO-2019118830-A1 | HSP90-TARGETING CONJUGATES AND FORMULATIONS THEREOF | TARVEDA THERAPEUTICS, INC. (US) | 2019-06-20 | — | — | WO | disclosed |