⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27699661 | 1.00 | — | — | |
| SCHEMBL27680540 | 1.00 | — | — | |
| SCHEMBL27699660 | 1.00 | — | — | |
| SCHEMBL3086841 | 0.77 | CA1 (0.38) | — | |
| SCHEMBL21564147 | 0.77 | — | — | |
| SCHEMBL4199159 | 0.75 | CA1 (0.32) | — | |
| SCHEMBL4199154 | 0.75 | CA1 (0.32) | — | |
| SCHEMBL4199156 | 0.75 | CA1 (0.32) | — | |
| SCHEMBL28347230 | 0.75 | — | — | |
| SCHEMBL7093108 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019118932-A1 | INHIBITORS OF FIBROBLAST ACTIVATION PROTEIN | Praxis Biotech LLC (US) | 2019-06-20 | — | — | WO | disclosed |