Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 11/20 | 0.67 |
| ▸ | ACE | P12821 | 7/20 | 0.67 |
| ▸ | MMEL1 | Q495T6 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sacubitril SCHEMBL18059569 | 0.94 | MME (0.77) | MMEACEMMEL1 | |
| Sacubitril SCHEMBL489040 | 0.94 | MME (0.77) | MMEACEMMEL1 | |
| Sacubitril SCHEMBL22420467 | 0.94 | MME (0.77) | MMEACEMMEL1 | |
| Sacubitril SCHEMBL2707112 | 0.94 | MME (0.77) | MMEACEMMEL1 | |
| Sacubitril SCHEMBL18574632 | 0.94 | MME (0.77) | MMEACEMMEL1 | |
| Sacubitril SCHEMBL18059568 | 0.94 | MME (0.77) | MMEACEMMEL1 | |
| Sacubitril SCHEMBL1908525 | 0.94 | MME (0.77) | MMEACEMMEL1 | |
| Sacubitril SCHEMBL8214132 | 0.94 | MME (0.77) | MMEACEMMEL1 | |
| Sacubitril SCHEMBL21239955 | 0.93 | MME (0.76) | MMEACEMMEL1 | |
| Sacubitril SCHEMBL21239958 | 0.93 | MME (0.76) | MMEACEMMEL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3218351-B1 | A METHOD FOR THE PREPARATION, ISOLATION AND PURIFICATION OF PHARMACEUTICALLY APPLICABLE FORMS OF AHU-377 | ZENTIVA KS (CZ) | 2019-06-19 | — | — | EP | disclosed |