Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.69 |
| ▸ | ALK | Q9UM73 | 14/20 | 0.60 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.53 |
| ▸ | MET | P08581 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21150888 | 0.91 | EGFR (0.57) | EGFRALKMET | |
| SCHEMBL21846981 | 0.82 | EGFR (1.00) | EGFRALKPTK2MET | |
| SCHEMBL19867181 | 0.81 | ALK (0.61) | EGFRALKMET | |
| SCHEMBL21150899 | 0.80 | ALK (0.49) | EGFRALKMET | |
| SCHEMBL21150641 | 0.79 | EGFR (0.56) | EGFRALK | |
| SCHEMBL21099419 | 0.78 | ALK (0.72) | EGFRALKMET | |
| SCHEMBL19867195 | 0.77 | PTK2 (0.53) | EGFRALKPTK2MET | |
| SCHEMBL21099577 | 0.77 | ALK (0.51) | EGFRALKPTK2MET | |
| SCHEMBL21099668 | 0.77 | PTK2 (0.58) | EGFRALKPTK2MET | |
| SCHEMBL19867264 | 0.77 | ALK (0.51) | EGFRALKPTK2MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3498716-A1 | THIENOPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION, AND APPLICATIONS | Hongyun Biotech Co., Ltd. (CN) | 2019-06-19 | — | — | EP | disclosed |