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SCHEMBL21099709

SCHEMBL21099709

CC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CCCNC(=O)CCC(NC(=O)CC[C@H](NC(=O)CCCCCCCCCCCCCCCCC(=O)O)C(=O)O)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.67
▸ NOD1 Q9Y239 3/20 0.47
▸ CCKAR P32238 3/20 0.42
▸ CCKBR P32239 3/20 0.42
▸ FOLH1 Q04609 3/20 0.42
▸ GLO1 Q04760 1/20 0.41
▸ EPHX2 P34913 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21242829 1.00 GLP1R (0.67) GLP1RNOD1CCKARCCKBRFOLH1
SCHEMBL20911267 0.98 GLP1R (0.67) GLP1RNOD1CCKARCCKBRFOLH1
SCHEMBL24198476 0.98 GLP1R (0.67) GLP1RNOD1CCKARCCKBRFOLH1
SCHEMBL17682353 0.98 GLP1R (0.67) GLP1RNOD1CCKARCCKBRFOLH1
SCHEMBL24899310 0.98 GLP1R (0.67) GLP1RNOD1CCKARCCKBRFOLH1
SCHEMBL24284196 0.98 GLP1R (0.67) GLP1RNOD1CCKARCCKBRFOLH1
SCHEMBL23051891 0.98 GLP1R (0.67) GLP1RNOD1CCKARCCKBRFOLH1
SCHEMBL17570497 0.98 GLP1R (0.67) GLP1RNOD1CCKARCCKBRFOLH1
SCHEMBL17570507 0.98 GLP1R (0.67) GLP1RNOD1CCKARCCKBRFOLH1
SCHEMBL12674220 0.98 GLP1R (0.67) GLP1RNOD1CCKARCCKBRFOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2986313-B1 STABLE, PROTRACTED GLP-1/GLUCAGON RECEPTOR CO-AGONISTS FOR MEDICAL USE NOVO NORDISK AS (DK) 2019-06-12 — — EP disclosed