Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.70 |
| ▸ | CNR1 | P21554 | 1/20 | 0.70 |
| ▸ | ATM | Q13315 | 1/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.45 |
| ▸ | MMP1 | P03956 | 2/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | CETP | P11597 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.41 |
| ▸ | CCR8 | P51685 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21100582 | 1.00 | TDP1 (0.70) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL11217669 | 1.00 | TDP1 (0.70) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL21820776 | 0.91 | TDP1 (0.74) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL11009788 | 0.90 | TDP1 (0.71) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL11314750 | 0.89 | TDP1 (0.72) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL6439660 | 0.87 | TDP1 (0.70) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL6048301 | 0.86 | TDP1 (0.69) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL11318174 | 0.86 | TDP1 (0.72) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL2112591 | 0.85 | TDP1 (0.74) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL11418777 | 0.85 | TDP1 (0.67) | TDP1LMNAADRA2ACNR1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10647655-B2 | Method for the synthesis of permethrin | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) | 2020-05-12 | — | — | US | disclosed |
| US-20190194118-A1 | IMPROVED METHOD FOR THE SYNTHESIS OF PERMETHRIN | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) | 2019-06-27 | — | — | US | disclosed |
| US-20190190720-A1 | SECURING AN ITEM OF DEVICE USE INFORMATION OF A DEVICE | SIEMENS AKTIENGESELLSCHAFT (DE) | 2019-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10647655-B2 | Method for the synthesis of permethrin | NUP188, CYP2E1, AQP4 | TDP1 2093/4885LMNA 2817/4885ADRA2A 4416/4885 |
| US-20190194118-A1 | IMPROVED METHOD FOR THE SYNTHESIS OF PERMETHRIN | CYP51A1, CYP4F3, CYP4F2 | TDP1 2598/4885LMNA 4054/4885ADRA2A 4542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.