Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 19/20 | 0.74 |
| ▸ | MAOB | P27338 | 4/20 | 0.74 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19384019 | 0.85 | KDM1A (1.00) | KDM1AMAOB | |
| SCHEMBL20656883 | 0.85 | KDM1A (1.00) | KDM1AMAOB | |
| SCHEMBL18817631 | 0.78 | KDM1A (0.81) | KDM1AMAOBDRD2HTR2ASLC6A4 | |
| SCHEMBL15425027 | 0.77 | KDM1A (0.73) | KDM1AMAOBDRD2HTR2ASLC6A4 | |
| SCHEMBL16309046 | 0.77 | KDM1A (0.73) | KDM1AMAOBDRD2HTR2ASLC6A4 | |
| SCHEMBL15425028 | 0.77 | KDM1A (0.73) | KDM1AMAOBDRD2HTR2ASLC6A4 | |
| SCHEMBL16309047 | 0.77 | KDM1A (0.73) | KDM1AMAOBDRD2HTR2ASLC6A4 | |
| SCHEMBL15423786 | 0.77 | KDM1A (0.73) | KDM1AMAOBDRD2HTR2ASLC6A4 | |
| SCHEMBL15423787 | 0.77 | KDM1A (0.73) | KDM1AMAOBDRD2HTR2ASLC6A4 | |
| SCHEMBL12813922 | 0.77 | KDM1A (0.73) | KDM1AMAOBDRD2HTR2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2688568-B1 | CYCLOPROPYLAMINES AS LSD1 INHIBITORS | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2019-06-19 | — | — | EP | disclosed |