SCHEMBL21101101

SCHEMBL21101101

NCCOCCOCCO[C@H]1OC(COC(=O)c2ccccc2)[C@@H](OC(=O)c2ccccc2)C(OC(=O)c2ccccc2)C1OC(=O)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ USP2 O75604 2/20 0.50
▸ MEN1 O00255 1/20 0.50
▸ POLB P06746 1/20 0.50
▸ KMT2A Q03164 1/20 0.50
▸ PTPN1 P18031 6/20 0.48
▸ CA1 P00915 2/20 0.47
▸ CA2 P00918 2/20 0.47
▸ TMPRSS2 O15393 1/20 0.47
▸ PDE5A O76074 1/20 0.47
▸ HMGCR P04035 1/20 0.47
▸ CYP1A2 P05177 1/20 0.47
▸ LCK P06239 1/20 0.47
▸ FYN P06241 1/20 0.47
▸ HSPD1 P10809 1/20 0.47
▸ CYP2C9 P11712 1/20 0.47
▸ CA6 P23280 1/20 0.47
▸ TBXAS1 P24557 1/20 0.47
▸ MAPK3 P27361 1/20 0.47
▸ MAPK1 P28482 1/20 0.47
▸ HSPE1 P61604 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14978161 1.00 USP2 (0.50) USP2MEN1POLBKMT2APTPN1
SCHEMBL10177584 1.00 USP2 (0.50) USP2MEN1POLBKMT2APTPN1
SCHEMBL6220068 0.92 PTPN1 (0.53) USP2MEN1POLBKMT2APTPN1
SCHEMBL6220071 0.92 PTPN1 (0.53) USP2MEN1POLBKMT2APTPN1
SCHEMBL18654302 0.91 PTPN1 (0.50) USP2MEN1POLBKMT2APTPN1
SCHEMBL8354052 0.90 PTPN1 (0.49) USP2MEN1POLBKMT2APTPN1
SCHEMBL18755602 0.90 PTPN1 (0.49) USP2MEN1POLBKMT2APTPN1
SCHEMBL15833624 0.89 PTPN1 (0.48) USP2MEN1POLBKMT2APTPN1
SCHEMBL15833448 0.89 PTPN1 (0.48) USP2MEN1POLBKMT2APTPN1
SCHEMBL15833435 0.89 PTPN1 (0.48) USP2MEN1POLBKMT2APTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11666653-B2 Carbohydrate conjugates as delivery agents for oligonucleotides ALNYLAM PHARMACEUTICALS, INC. (US) 2023-06-06 — — US disclosed
US-20220143189-A1 CARBOHYDRATE CONJUGATES AS DELIVERY AGENTS FOR OLIGONUCLEOTIDES BANK OF AMERICA, N.A. 2022-05-12 — — US disclosed
US-11110174-B2 Carbohydrate conjugates as delivery agents for oligonucleotides ALNYLAM PHARMACEUTICALS, INC. (US) 2021-09-07 — — US disclosed
US-10806791-B2 Carbohydrate conjugates as delivery agents for oligonucleotides ALNYLAM PHARMACEUTICALS, INC. (US) 2020-10-20 — — US disclosed
US-20200297853-A1 CARBOHYDRATE CONJUGATES AS DELIVERY AGENTS FOR OLIGONUCLEOTIDES BANK OF AMERICA, N.A. 2020-09-24 — — US disclosed
US-20190184018-A1 CARBOHYDRATE CONJUGATES AS DELIVERY AGENTS FOR OLIGONUCLEOTIDES BANK OF AMERICA, N.A. 2019-06-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190184018-A1 CARBOHYDRATE CONJUGATES AS DELIVERY AGENTS FOR OLIGONUCLEOTIDES SLC2A2, SLC2A8, SLC2A1 USP2 3449/4885MEN1 2703/4885POLB 1646/4885
US-20200297853-A1 CARBOHYDRATE CONJUGATES AS DELIVERY AGENTS FOR OLIGONUCLEOTIDES SLC2A2, SLC2A8, SLC2A1 USP2 3449/4885MEN1 2703/4885POLB 1646/4885
US-11666653-B2 Carbohydrate conjugates as delivery agents for oligonucleotides HAVCR2, B3GAT3, CSGALNACT1 USP2 3132/4885MEN1 1495/4885POLB 2228/4885
US-20220143189-A1 CARBOHYDRATE CONJUGATES AS DELIVERY AGENTS FOR OLIGONUCLEOTIDES HAVCR2, B3GAT3, CSGALNACT1 USP2 3132/4885MEN1 1495/4885POLB 2228/4885
US-10806791-B2 Carbohydrate conjugates as delivery agents for oligonucleotides SLC2A2, SLC2A8, SLC2A1 USP2 3449/4885MEN1 2703/4885POLB 1646/4885
US-11110174-B2 Carbohydrate conjugates as delivery agents for oligonucleotides SLC2A2, SLC2A8, SLC2A1 USP2 3449/4885MEN1 2703/4885POLB 1646/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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