Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | KDM1A | O60341 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.51 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CHKA | P35790 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21100969 | 1.00 | KDM4E (0.56) | KDM4EKDM1AKMT2AMEN1CHRM4 | |
| SCHEMBL21101175 | 0.88 | KDM1A (0.58) | KDM1AKMT2AMEN1 | |
| SCHEMBL16130141 | 0.85 | KDM4E (0.64) | KDM4EKDM1AKMT2AMEN1CHRM4 | |
| SCHEMBL20257081 | 0.82 | KDM4E (0.65) | KDM4EKDM1AKMT2AMEN1CHRM4 | |
| SCHEMBL16309046 | 0.82 | KDM1A (0.73) | KDM1A | |
| SCHEMBL15425027 | 0.82 | KDM1A (0.73) | KDM1A | |
| SCHEMBL15423787 | 0.82 | KDM1A (0.73) | KDM1A | |
| SCHEMBL15423786 | 0.82 | KDM1A (0.73) | KDM1A | |
| SCHEMBL16309047 | 0.82 | KDM1A (0.73) | KDM1A | |
| SCHEMBL15425028 | 0.82 | KDM1A (0.73) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2688568-B1 | CYCLOPROPYLAMINES AS LSD1 INHIBITORS | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2019-06-19 | — | — | EP | disclosed |