Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 12/20 | 0.68 |
| ▸ | MAOA | P21397 | 10/20 | 0.68 |
| ▸ | MAOB | P27338 | 10/20 | 0.68 |
| ▸ | RCOR1 | Q9UKL0 | 3/20 | 0.68 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.53 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.53 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31187352 | 0.86 | KDM1A (0.51) | KDM1AMAOAMAOBRCOR1KDM1B | |
| SCHEMBL15789116 | 0.86 | KDM1A (0.68) | KDM1AMAOAMAOBRCOR1KDM1B | |
| SCHEMBL15789119 | 0.86 | KDM1A (0.68) | KDM1AMAOAMAOBRCOR1KDM1B | |
| SCHEMBL22335069 | 0.83 | KDM1A (0.77) | KDM1AMAOAMAOBRCOR1KDM1B | |
| SCHEMBL15787819 | 0.83 | KDM1A (0.77) | KDM1AMAOAMAOBRCOR1KDM1B | |
| SCHEMBL15789029 | 0.82 | KDM1A (0.62) | KDM1AMAOAMAOBRCOR1KDM1B | |
| SCHEMBL14701059 | 0.82 | KDM1A (0.62) | KDM1AMAOAMAOBRCOR1KDM1B | |
| SCHEMBL14701055 | 0.82 | KDM1A (0.69) | KDM1AMAOAMAOBRCOR1KDM1B | |
| SCHEMBL15789154 | 0.82 | KDM1A (0.69) | KDM1AMAOAMAOBRCOR1KDM1B | |
| SCHEMBL15789077 | 0.81 | KDM1A (0.72) | KDM1AMAOAMAOBRCOR1KDM1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2688568-B1 | CYCLOPROPYLAMINES AS LSD1 INHIBITORS | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2019-06-19 | — | — | EP | disclosed |