Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18419018 | 0.91 | TSHR (0.47) | TSHRTDP1 | |
| SCHEMBL679176 | 0.89 | TSHR (0.67) | TSHRTDP1ALDH1A1 | |
| SCHEMBL18419017 | 0.87 | TSHR (0.57) | TSHRTDP1ALDH1A1 | |
| SCHEMBL13573771 | 0.81 | TSHR (0.57) | TSHRALDH1A1 | |
| SCHEMBL12367256 | 0.79 | TSHR (0.52) | TSHRTDP1 | |
| SCHEMBL13573753 | 0.78 | TSHR (0.54) | TSHRALDH1A1 | |
| SCHEMBL19344489 | 0.77 | TSHR (0.58) | TSHRTDP1 | |
| SCHEMBL1022340 | 0.77 | TSHR (0.60) | TSHRTDP1 | |
| SCHEMBL1021679 | 0.77 | TSHR (0.60) | TSHRTDP1 | |
| SCHEMBL16846588 | 0.76 | TSHR (0.49) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10322069-B2 | Restorative resin compositions and methods of use | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2019-06-18 | — | — | US | disclosed |