Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.68 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.58 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.58 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.58 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11195138 | 0.94 | CLEC4M (0.76) | CLEC4MKDM4EGABRA1GABRB2GABRB1 | |
| SCHEMBL28287784 | 0.86 | CLEC4M (0.82) | CLEC4MKDM4EGABRA1GABRB2GABRB1 | |
| SCHEMBL1244789 | 0.85 | CLEC4M (0.80) | CLEC4MKDM4EGABRA1GABRB2GABRB1 | |
| SCHEMBL22492440 | 0.85 | CLEC4M (0.80) | CLEC4MKDM4EGABRA1GABRB2GABRB1 | |
| SCHEMBL16341803 | 0.84 | CLEC4M (0.78) | CLEC4MKDM4EGABRA1GABRB2GABRB1 | |
| SCHEMBL1126279 | 0.84 | CLEC4M (0.78) | CLEC4MKDM4EGABRA1GABRB2GABRB1 | |
| SCHEMBL11195663 | 0.84 | CLEC4M (0.78) | CLEC4MKDM4EGABRA1GABRB2GABRB1 | |
| SCHEMBL774558 | 0.83 | CLEC4M (0.76) | CLEC4MKDM4EGABRA1GABRB2GABRB1 | |
| SCHEMBL5133700 | 0.83 | CLEC4M (0.71) | CLEC4MKDM4EGABRA1GABRB2GABRB1 | |
| SCHEMBL28289147 | 0.82 | CLEC4M (0.74) | CLEC4MKDM4EGABRA1GABRB2GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111448192-B | Process for preparing anthelmintic 4-amino-quinoline-3-carboxamide derivatives | 拜耳动物保健有限责任公司 | 2024-04-12 | — | — | CN | disclosed |
| US-11505544-B2 | Process for preparing antihelmintic 4-amino-quinoline-3-carboxamide derivatives | BAYER ANIMAL HEALTH GMBH (DE) | 2022-11-22 | — | — | US | disclosed |
| US-20200308153-A1 | PROCESS FOR PREPARING ANTIHELMINTIC 4-AMINO-QUINOLINE-3-CARBOXAMIDE DERIVATIVES | BAYER ANIMAL HEALTH GMBH (DE) | 2020-10-01 | — | — | US | disclosed |
| US-20200308153-A1 | PROCESS FOR PREPARING ANTIHELMINTIC 4-AMINO-QUINOLINE-3-CARBOXAMIDE DERIVATIVES | BAYER ANIMAL HEALTH GMBH (DE) | 2020-10-01 | — | — | US | disclosed |
| CN-111448192-A | Process for preparing anthelmintic 4-amino-quinoline-3-carboxamide derivatives | 拜耳动物保健有限责任公司 | 2020-07-24 | — | — | CN | disclosed |
| WO-2019115768-A1 | PROCESS FOR PREPARING ANTIHELMINTIC 4-AMINO-QUINOLINE-3-CARBOXAMIDE DERIVATIVES | BAYER ANIMAL HEALTH GMBH (DE) | 2019-06-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11505544-B2 | Process for preparing antihelmintic 4-amino-quinoline-3-carboxamide derivatives | HRH4, HRH2, HRH1 | CLEC4M 2670/4885KDM4E 666/4885GABRA1 2162/4885 |
| US-20200308153-A1 | PROCESS FOR PREPARING ANTIHELMINTIC 4-AMINO-QUINOLINE-3-CARBOXAMIDE DERIVATIVES | HRH4, HRH2, HRH1 | CLEC4M 2670/4885KDM4E 666/4885GABRA1 2162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.