SCHEMBL21101475

SCHEMBL21101475

N#CC1CCCN1C(=O)CNC=O

nearest known ligand 0.69

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 20/20 0.69
DPP8 Q6V1X1 2/20 0.65
DPP9 Q86TI2 2/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4419343 0.87 DPP4 (0.82) DPP4DPP8DPP9
SCHEMBL4419347 0.87 DPP4 (0.82) DPP4DPP8DPP9
SCHEMBL4419337 0.87 DPP4 (0.82) DPP4DPP8DPP9
SCHEMBL5070890 0.85 DPP4 (0.75) DPP4DPP8DPP9
SCHEMBL5066712 0.85 DPP4 (0.75) DPP4DPP8DPP9
SCHEMBL13057149 0.81 DPP4 (0.70) DPP4DPP8DPP9
SCHEMBL8261098 0.81 DPP4 (0.73) DPP4DPP8DPP9
SCHEMBL18098613 0.81 DPP4 (0.70) DPP4DPP8DPP9
SCHEMBL10051994 0.81 DPP4 (0.70) DPP4DPP8DPP9
SCHEMBL11381705 0.81 DPP4 (0.46) DPP4DPP8DPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2804859-B1 NOVEL FAP INHIBITORS UNIV ANTWERPEN (BE) 2019-06-12 EP disclosed