Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 6/20 | 1.00 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.72 |
| ▸ | NCF1 | P14598 | 1/20 | 0.53 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | CCNC | P24863 | 1/20 | 0.44 |
| ▸ | CDK8 | P49336 | 1/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | GAK | O14976 | 1/20 | 0.42 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.42 |
| ▸ | COQ8A | Q8NI60 | 1/20 | 0.42 |
| ▸ | NLK | Q9UBE8 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL596040 | 0.84 | NR4A2 (1.00) | NR4A2SOS2NCF1CYP1A2FERMT2 | |
| SCHEMBL1888577 | 0.79 | NR4A2 (0.66) | NR4A2SOS2PARP1CCNCCDK8 | |
| SCHEMBL30051309 | 0.79 | NR4A2 (0.66) | NR4A2SOS2PARP1CCNCCDK8 | |
| SCHEMBL4823097 | 0.79 | NR4A2 (0.66) | NR4A2SOS2NCF1PARP1ALDH1A1 | |
| SCHEMBL30210360 | 0.79 | NR4A2 (0.66) | NR4A2SOS2NCF1PARP1ALDH1A1 | |
| SCHEMBL28957472 | 0.78 | NR4A2 (0.62) | NR4A2SOS2NCF1CCNCCDK8 | |
| Bromide SCHEMBL5989384 | 0.78 | NR4A2 (0.63) | NR4A2SOS2NCF1PARP1ALDH1A1 | |
| SCHEMBL24150113 | 0.76 | NR4A2 (0.61) | NR4A2SOS2NCF1OPRL1ALDH1A1 | |
| SCHEMBL827782 | 0.76 | NR4A2 (0.61) | NR4A2SOS2PARP1CCNCCDK8 | |
| SCHEMBL11772187 | 0.76 | NR4A2 (0.61) | NR4A2SOS2PARP1CCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3481806-B1 | 4-ANILINO-QUINOLINE COMPOUNDS AS ANTI-CANCER AGENTS | INST NAT SANTE RECH MED (FR) | 2023-06-07 | — | — | EP | claimed |
| EP-2804859-B1 | NOVEL FAP INHIBITORS | UNIV ANTWERPEN (BE) | 2019-06-12 | — | — | EP | disclosed |